It happened around 2:30am Thursday on LA 3132.
Shreveport Police tell NBC 6 News an SUV hit a guardrail, drove across traffic, and rolled over.
The driver was trapped inside the car with serious injuries.
After being extricated, he was Life Air Rescued to a local hospital.
This is a developing story, stay with NBC 6 News for the latest updates.
Copyright 2016 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.