The victims have been identified as Jimmy Crisenberry, 66, of Allen, Okolahoma, and Judy Milburn, 52, of Oklahoma City, Oklahoma. Crisenberry was driving their vehicle.
Two other truck drivers were transported to Longview Regional, where they were treated and released.
Officials tell KETK the accident involved five semi trucks.
Two people are dead following a multi-vehicle wreck on Interstate 20.
The westbound lanes of I-20 have been shut down as crews work to clear the accident in Harrison County.
Authorities say the accident happened between mile markers 599 and 600.
Officials say the accident involves multiple semi trucks.
Traffic is being re-routed as a result.
A crew from our sister station, KETK, is on scene and will continue to update this story as more information becomes available.